Daño neurológico en infecciones por SARS-CoV-2: Neurological damage in SARS-CoV-2 infections

The current Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic has severely impacted the economy and health care system in more than 180 countries around the world in an unprecedented event, which since its inception has resulted in countless case reports focusing on the potentially fatal systemic and respiratory manifestations of the disease. However, the full extent of possible neurological manifestations caused by this new virus is not yet known. Understanding the interaction of SARS-CoV-2 with the nervous system is essential to assessing likely short- and long-term pathologic consequences. This review seeks to gather and discuss evidence on the occurrence of neurological manifestations and/or nervous system involvement in SARS- CoV-2 infected patients.La actual pandemia producida por el coronavirus 2 del síndrome respiratorio agudo severo (SARS-CoV-2), ha impactado gravemente la economía y el sistema de salud en más de 190 países de todo el mundo en un evento sin precedentes, que desde su inicio ha dado lugar a innumerables informes de casos centrados en las manifestaciones sistémicas y respiratorias potencialmente mortales de la enfermedad. Sin embargo, aún no se conoce por completo el alcance de las posibles manifestaciones neurológicas causadas por este 2 nuevo virus. Comprender la interacción del SARS-CoV-2 con el sistema nervioso es esencial para evaluar las probables consecuencias patológicas a corto y largo plazo. Esta revisión busca reunir y discutir la evidencia sobre la ocurrencia de manifestaciones neurológicas y/o compromiso del sistema nervioso en pacientes infectados con SARS- CoV-2

IDENTIFICACIÓN Y CARACTERIZACIÓN DE LAS ARCILLAS DE LA CIUDAD DE HUÁNUCO

Los cinco sectores del Asentamiento Humano San Luis, en Huánuco, se localizan sobre una geoforma denominada “piedemonte”, bajo el cerro San Cristóbal, con una litografía de rocas metamórficas esquistosas del Complejo del Marañón. Las rocas, por los procesos del intemperismo dan origen a suelos residuales que caen como aluviales y coluviales. Estos poseen minerales de Sílice (SiO2) en un 95%, que combinan con otros elementos minerales: aluminio, magnesio, hierro, formando materiales de gradación fina llamadas arcillas, cuyo comportamiento expansivo y de baja capacidad de soporte, al ser saturados, son de preocupación para la ingeniería civil. Con el objetivo de evaluar su estratificación y caracterización, se han realizado sondeos, ensayos estándar de clasificación en los sectores I, II, III y V, además de aplicar el esquema de Geopedología de Sinck para establecer la relación entre fisiografía y pedología. Se concluye elaborando el mapa de distribución estratigráfica usando el software ARCGIS, caracterizando los espesores de los estratos, que varían entre menos de uno hasta tres metros. También se verificó que su grado de expansión es bajo y su capacidad de soporte es regular

Fine Time Measurement for the Internet of Things: A Practical Approach Using ESP32

[Abstract]: In the world of Internet of Things (IoT), obtaining the physical location of devices has always been a task of great interest for developing increasingly complex location-based services (LBS). That is why in recent years wireless communication standards have been incorporating new additions focused on providing localization mechanisms to technologies widely used in the IoT world, such as Wi-Fi or Bluetooth. In particular, the IEEE 802.11-2016 Wi-Fi standard introduced ranging estimation between two devices through the so-called fine time measurement (FTM) protocol, defined by the IEEE 802.11mc. FTM is not yet widespread in the IoT field, but commercial modules capable of offering this functionality at a reasonable price are starting to appear. In early 2021, the most widespread system on a chip (SOC) family among IoT devices, the ESP32-XX series, added support for this Wi-Fi standard, enabling, for the first time, the use of a standard designed for location-based systems. This article analyzes the performance of this FTM implementation by carrying out and studying several measurement campaigns in different indoor and outdoor scenarios. Additionally, this work proposes an alternative real-time implementation for distance estimation inside the ESP32 using an approach based on machine learning. Such an implementation is successfully validated in a scenario totally different than those considered for the training and test sets. Finally, both the measurement sets and the developed software are available to the scientific community

An overview of IoT architectures, technologies, and existing open-source projects

Financiado para publicación en acceso aberto: Universidade da Coruña/CISUG[Abstract]: Today’s needs for monitoring and control of different devices in organizations require an Internet of Things (IoT) platform that can integrate heterogeneous elements provided by multiple vendors and using different protocols, data formats and communication technologies. This article provides a comprehensive review of all the architectures, technologies, protocols and data formats most commonly used by existing IoT platforms. On this basis, a comparative analysis of the most widely used open source IoT platforms is presented. This exhaustive comparison is based on multiple characteristics that will be essential to select the platform that best suits the needs of each organization.This research/work has been supported by GAIN (Galician Innovation Agency) and the Regional Ministry of Economy, Employment and Industry, Xunta de Galicia under grant COV20/00604 through the ERDF Galicia 2014-2020; and by grant PID2019-104958RB-C42 (ADELE) funded by MCIN/AEI/10.13039/501100011033 . Funding for open access charge: Universidade da Coruña/CISUG.Xunta de Galicia; COV20/0060

Informe de la expedición científica CIMAR-COCO-I

El proyecto “Conocimiento y gestión de medios marinos y coralinos del Área de Conservación Marina Isla del Coco” fue financiado por el Fondo Francés para el Medio Ambiente Mundial y la Universidad de Costa Rica. Del 9 al 20 de octubre del 2007 un grupo de científicos del Centro de Investigación en Ciencias del Mar y Limnología (CIMAR) de la Universidad de Costa Rica, en conjunto con personal de otros centros de investigación realizaron la Expedición CIMAR-COCO-I. Para esta expedición se utilizó el barco de MarViva, MV Phoenix I, con un apoyo excelente de la tripulación. La finalidad de esta expedición fue iniciar los diferentes componentes de campo del proyecto.Fondo Francés para el Medio Ambiente Mundial y la Universidad de Costa RicaUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Básicas::Centro de Investigación en Ciencias del Mar y Limnología (CIMAR

Ahora / Ara

La cinquena edició del microrelatari per l’eradicació de la violència contra les dones de l’Institut Universitari d’Estudis Feministes i de Gènere «Purificación Escribano» de la Universitat Jaume I vol ser una declaració d’esperança. Aquest és el moment en el qual les dones (i els homes) hem de fer un pas endavant i eliminar la violència sistèmica contra les dones. Ara és el moment de denunciar el masclisme i els micromasclismes començant a construir una societat més igualitària. Cadascun dels relats del llibre és una denúncia i una declaració que ens encamina cap a un món millor

Anales del III Congreso Internacional de Vivienda y Ciudad "Debate en torno a la nueva agenda urbana"

Acta de congresoEl III Congreso Internacional de Vivienda y Ciudad “Debates en torno a la NUEVa Agenda Urbana”, ha sido una apuesta de alto compromiso por acercar los debates centrales y urgentes que tensionan el pleno ejercicio del derecho a la ciudad. Para ello las instituciones organizadoras (INVIHAB –Instituto de Investigación de Vivienda y Hábitat y MGyDH-Maestría en Gestión y Desarrollo Habitacional-1), hemos convidado un espacio que se concretó con potencia en un debate transdisciplinario. Convocó a intelectuales de prestigio internacional, investigadores, académicos y gestores estatales, y en una metodología de innovación articuló las voces académicas con las de las organizaciones sociales y/o barriales en el Foro de las Organizaciones Sociales que tuvo su espacio propio para dar voz a quienes están trabajando en los desafíos para garantizar los derechos a la vivienda y los bienes urbanos en nuestras ciudades del Siglo XXI

Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries